Belated congratulations to Rob Finn, who has moved to EMBL-EBI to lead the Protein Families team. The HMMER web services pilot project that HHMI has funded at Janelia, under Rob's leadership, is now in transition to EBI, and Rob and I will write more about this in the future.
Slightly-less-belated …
The Wellcome Trust Sanger Institute is hosting a meeting on computational RNA biology on 11-13 November 2014, co-organized by Alex Bateman (EMBL-EBI), Anton Enright (EMBL-EBI), Mihaela Zavolan (University of Basel), and myself. I'm especially keen on this meeting because we've invited several people who have been active in developing computational …
Janelia has a scientific director-level position open in our computation and technology group:
"The Janelia Farm Research Campus of the Howard Hughes Medical Institute seeks an exceptional individual to lead a world-class technology effort in advanced computation, data analysis, and instrumentation design and fabrication. The Director of Janelia’s Advanced …
The HMMER dev team is happy to announce an upgrade release of HMMER3, release 3.1. A beta test version of the code is publicly available as a tarball available for download, or from hmmer.org, where you'll also find precompiled binary releases for Mac and Linux.
HMMER 3.1 …
Rob Finn's HMMER web services team is expanding. We're looking for people to apply to two new positions to help Rob and Jody push forward on some important ideas for our services. We're pushing in the direction of using more phylogenetic information (species trees) as we compute database homology searches …
I've always been jealous of the Eisen brothers. Finally, some parity. Congratulations to my brother Nicholas who passed his PhD defense in synthetic organic chemistry at University of Connecticut yesterday! A momentous occasion. Now for some interdisciplinary synthetic organic computational genomics.
Registration is open for a conference on "Biological sequence analysis and probabilistic models", 24-27 March 2013, here at Janelia Farm. Katie Pollard (UCSF), Adam Siepel (Cornell), and I are the co-organizers. Janelia Farm conferences are small (\~50 people), a nice size for conversation and thought. We're likely to select about …
A friend just sent this wonderful video of my favorite city, to make me wistful. We still get our coffee shipped from Kaldi's, our old neighborhood coffee shop. The saying in the lab was "St. Louis: better than you'd think." Go Cards!
Here is St. Louis from Anastasis Films
So I read in the newspaper this week that the ENCODE project has disproven the idea of junk DNA. I sure wish I'd gotten the memo, because this week a collaboration of labs led by myself, Arian Smit, and Jerzy Jurka just released a new data resource that annotates nearly …
We're happy to announce the release of Dfam 1.0, a set of profile HMMs for genomic DNA annotation of transposable elements. This essentially constitutes an upgrade of repeat element annotation from using searches with single sequence consensuses to using searches with profile HMMs, now that the HMMER3 project has …