In 2005, the New Yorker published a remarkable article by Margaret Talbot called The Auteur of Anime, about the Japanese director Hayao Miyazaki.
At that time, I hadn't heard of Miyazaki or his Studio Ghibli, even though almost all of his movies have been brought to the US market and …
The final HMMER3 beta test release is available for download as a tarball. It includes precompiled binaries for Intel/Linux systems, both 64-bit (x86_84) and 32-bit (ia32) platforms, and you may just copy these into some directory in your \$PATH if you like. If the precompiled versions don't work for …
Do not go gentle into that good night,
Old age should burn and rave at close of day;
Rage, rage against the dying of the light.Dylan Thomas
Every time I shake someone's hand, I think of my grandfather.
I was maybe six years old when I limply shook Daz's …
The truth will set you free. But not until it is finished with you.
David Foster Wallace, Infinite Jest
With the release of Pfam 24, HMMER3 beta test code has been pressed into service just a bit earlier than we're comfortable with. Though the 3.0b2 code seems to be …
Writing and drawing are slow, deliberate activities, so I tried to keep distractions to an absolute minimum, and I did everything myself. I liked this control, as it fostered a sense of craftsmanship. There was great personal satisfaction in attending to detail and quality, and I remain very proud of …
This is wrong on so many levels. I taught two of these young whippersnappers computational biology at WashU -- I should've stopped them when I had a chance. (I hope that old dude at the end isn't supposed to be me.)
An Interview With Cofactor Genomics
Some bugs crept through testing and into the 3.0b1 release of HMMER3. They're fixed, and the link in the "3.0b1" release post below was quietly updated to the 3.0b2 tarball available for download on our FTP site.
I fixed a bug with the new code that deals …
it is not necessary to accept everything as true, one must only accept it as necessary.
Franz Kafka, The Trial
As the unearthly whine of the Janelia compute cluster subsides after testing the beta1 release, power and lights are flickering back to life in Virginia, and I have a quiet …
The alpha test is complete, and the beta test phase begins today. HMMER3 beta test code is publicly available as a tarball available for download on our FTP site. Besides source code, the tarball also includes a binaries/ subdirectory with precompiled binaries for Intel/Linux systems, both 64-bit (in binaries …
There are two ways of spreading light: to be the candle or the mirror that reflects it.
Edith Wharton, Vesalius in Zante
On April 14, the US Patent and Trademark Office awarded us a trademark on HMMER. This is a good moment to explain how we plan to deal with …